| No URTI (n = 65) | URTI (n = 67) | p value1 |
---|
Pseudomonas
2
| 0.04 (0.01–0.49) | 0.04 (0.01–0.14) | 0.348 |
Moraxella
|
7.51
(0.06–37.94)
|
30.55
(0.31–48.14)
|
0.044
|
Staphylococcus
2
| 0.04 (0.01–0.17) | 0.02 (0.01–0.17) | 0.458 |
Dolosigranulum
|
32.75
(9.46–48.89)
|
15.08
(4.25–32.09)
|
0.044
|
Streptococcus
2
|
0.55
(0.12–3.41)
|
1.57
(0.29–7.57)
|
0.040
|
Corynebacterium
|
13.54
(3.53–34.10)
|
2.61
(0.80–14.55)
|
0.039
|
Haemophilus
2
|
0.04
(0.01–2.78)
|
0.81
(0.09–16.48)
|
0.002
|
- Data are median (interquartile range)
- 1p value calculated following multivariable linear regression adjusting for ethnicity, presence of URTI symptoms, exposure to household cigarette smoke, breastfeeding status, year of swab collection, season of swab collection, antibiotic use in the previous 2 weeks and sex. An interaction between vaccination status and ethnicity was included in models for Pseudomonas (p = 0.026), Dolosigranulum (p = 0.093), Streptococcus (p = 0.033) and Haemophilus (p = 0.029), but not in models for Moraxella (p = 0.945), Corynebacterium (p = 0.387) and Staphylococcus (p = 0.453)
- 2Log transformation of relative abundance was used in the linear regression models