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Table 2 Per cent median relative abundance (IQR) for the seven most common genera by vaccination status (overall), by ethnicity, and by vaccination status within each ethnic group

From: The association between pneumococcal vaccination, ethnicity, and the nasopharyngeal microbiota of children in Fiji

 

No PCV7

(n = 65)

PCV7

(n = 67)

p value1

iTaukei

(n = 67)

FID

(n = 65)

p value1

iTaukei

FID

 

No PCV7

(n = 33)

PCV7

(n = 34)

p value1

No PCV7

(n = 32)

PCV7

(n = 33)

p value1

Pseudomonas 2

0.04

(0.01–0.50)

0.03

(0.01–0.24)

0.212

0.04

(0.01–0.44)

0.04

(0.02–0.27)

0.122

0.04

(0.01–0.16)

0.03

(0.01–0.77)

0.208

0.06

(0.02–0.58)

0.03

(0.02–1.00)

0.090

Moraxella

28.73

(8.55–44.56)

33.19

(0.30–50.78)

0.823

29.33

(1.97–46.70)

0.20

(0.05–30.67)

0.004

28.73

(8.55–44.56)

33.19

(0.30–50.78)

0.927

0.11

(0.04–29.14)

1.44

(0.05–30.78)

0.690

Staphylococcus 2

0.02

(0.01–0.16)

0.02

(0.01–0.05)

0.887

0.02

(0.01–0.06)

0.06

(0.02–0.26)

0.026

0.02

(0.01–0.16)

0.02

(0.01–0.05)

0.738

0.06

(0.02–0.26)

0.06

(0.03–0.27)

0.403

Dolosigranulum

21.26

(6.07–32.46)

15.94

(4.80–36.53)

0.777

18.18

(6.02–32.93)

36.42

(13.80–51.38)

0.004

21.26

(6.07–32.46)

15.94

(4.80–36.53)

0.632

29.25

(10.35–49.37)

44.59

(30.62–55.11)

0.037

Streptococcus 2

1.02

(0.16–7.15)

0.59

(0.16–1.86)

0.030

0.88

(0.23–4.72)

0.62

(0.12–3.42)

0.085

2.02

(0.48–7.18)

0.52

(0.14–1.78)

0.022

0.56

(0.09–5.46)

0.62

(0.21–1.89)

0.438

Corynebacterium

6.95

(0.99–17.98)

3.71

(1.24–15.99)

0.916

4.83

(1.22–17.08)

17.92

(3.42–37.60)

0.003

6.95

(0.99–17.98)

3.71

(1.24–15.99)

0.735

10.39

(3.06–33.35)

24.05

(6.03–42.25)

0.314

Haemophilus 2

1.02

(0.04–8.32)

0.11

(0.02–9.33)

0.053

0.59

(0.03–9.17)

0.03

(0.01–0.39)

0.004

1.02

(0.04–8.32)

0.11

(0.02–9.33)

0.043

0.03

(0.01–0.30)

0.04

(0.01–0.86)

0.462

  1. Data are median (interquartile range)
  2. 1p value calculated following multivariable linear regression adjusting for ethnicity, symptoms of an upper respiratory tract infection, exposure to household cigarette smoke, breastfeeding status, year of swab collection, season of swab collection, antibiotic use in the previous two weeks and sex of the child. An interaction between vaccination status and ethnicity was included in models for Pseudomonas (p = 0.026), Dolosigranulum (p = 0.093), Streptococcus (p = 0.033) and Haemophilus (p = 0.029) but not in models for Moraxella (p = 0.945), Corynebacterium (p = 0.387) and Staphylococcus (p = 0.453)
  3. 2Log transformation of relative abundance was used in the linear regression models