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Table 2 Per cent median relative abundance (IQR) for the seven most common genera by vaccination status (overall), by ethnicity, and by vaccination status within each ethnic group

From: The association between pneumococcal vaccination, ethnicity, and the nasopharyngeal microbiota of children in Fiji

  No PCV7
(n = 65)
PCV7
(n = 67)
p value1 iTaukei
(n = 67)
FID
(n = 65)
p value1 iTaukei FID
  No PCV7
(n = 33)
PCV7
(n = 34)
p value1 No PCV7
(n = 32)
PCV7
(n = 33)
p value1
Pseudomonas 2 0.04
(0.01–0.50)
0.03
(0.01–0.24)
0.212 0.04
(0.01–0.44)
0.04
(0.02–0.27)
0.122 0.04
(0.01–0.16)
0.03
(0.01–0.77)
0.208 0.06
(0.02–0.58)
0.03
(0.02–1.00)
0.090
Moraxella 28.73
(8.55–44.56)
33.19
(0.30–50.78)
0.823 29.33
(1.97–46.70)
0.20
(0.05–30.67)
0.004 28.73
(8.55–44.56)
33.19
(0.30–50.78)
0.927 0.11
(0.04–29.14)
1.44
(0.05–30.78)
0.690
Staphylococcus 2 0.02
(0.01–0.16)
0.02
(0.01–0.05)
0.887 0.02
(0.01–0.06)
0.06
(0.02–0.26)
0.026 0.02
(0.01–0.16)
0.02
(0.01–0.05)
0.738 0.06
(0.02–0.26)
0.06
(0.03–0.27)
0.403
Dolosigranulum 21.26
(6.07–32.46)
15.94
(4.80–36.53)
0.777 18.18
(6.02–32.93)
36.42
(13.80–51.38)
0.004 21.26
(6.07–32.46)
15.94
(4.80–36.53)
0.632 29.25
(10.35–49.37)
44.59
(30.62–55.11)
0.037
Streptococcus 2 1.02
(0.16–7.15)
0.59
(0.16–1.86)
0.030 0.88
(0.23–4.72)
0.62
(0.12–3.42)
0.085 2.02
(0.48–7.18)
0.52
(0.14–1.78)
0.022 0.56
(0.09–5.46)
0.62
(0.21–1.89)
0.438
Corynebacterium 6.95
(0.99–17.98)
3.71
(1.24–15.99)
0.916 4.83
(1.22–17.08)
17.92
(3.42–37.60)
0.003 6.95
(0.99–17.98)
3.71
(1.24–15.99)
0.735 10.39
(3.06–33.35)
24.05
(6.03–42.25)
0.314
Haemophilus 2 1.02
(0.04–8.32)
0.11
(0.02–9.33)
0.053 0.59
(0.03–9.17)
0.03
(0.01–0.39)
0.004 1.02
(0.04–8.32)
0.11
(0.02–9.33)
0.043 0.03
(0.01–0.30)
0.04
(0.01–0.86)
0.462
  1. Data are median (interquartile range)
  2. 1p value calculated following multivariable linear regression adjusting for ethnicity, symptoms of an upper respiratory tract infection, exposure to household cigarette smoke, breastfeeding status, year of swab collection, season of swab collection, antibiotic use in the previous two weeks and sex of the child. An interaction between vaccination status and ethnicity was included in models for Pseudomonas (p = 0.026), Dolosigranulum (p = 0.093), Streptococcus (p = 0.033) and Haemophilus (p = 0.029) but not in models for Moraxella (p = 0.945), Corynebacterium (p = 0.387) and Staphylococcus (p = 0.453)
  3. 2Log transformation of relative abundance was used in the linear regression models