Fig. 4

Relative abundance (%) heatmap including all 132 samples. Sample clustering is shown on the left-hand side. Taxa with a relative abundance above 30% in at least one sample are shown at the bottom. Where multiple OTUs are from the same genus ‘.1’ has been used for subsequent OTUs. ‘Others’ represents the remaining taxa in each sample. Clusters for samples have been coloured to show clustered groups: Cluster 1 (shown in dark blue), Cluster 2 (shown in green) dominated by Moraxella, Cluster 3 (shown in yellow) dominated by Dolosigranulum, Cluster 4 (shown in purple) dominated by Dolosigranulum and Corynebacterium, Cluster 5 (shown in orange) dominated by Haemophilus, and Cluster 6 (shown in grey) dominated by Pseudomonas. The vaccination status (unvaccinated—blue; vaccinated—red), ethnicity (iTaukei—turquoise; FID—gold) and whether the child had any symptoms of an upper respiratory tract infection (no URTI—light blue; URTI—brown) are shown in bars on the right of the heatmap