Fig. 2

Distribution of Clusters of Orthologous Groups (COGs) in three bile samples from control group (H-04, H-05, and H-06). The results show the percentage of sequences assigned to different metabolic functions (relative to all sequenced microbes). Secondary metabolite biosynthesis includes antibiotics, pigments, and non-ribosomal peptides. Inorganic ion transport and metabolism includes phosphate, sulfate, and various cation transporters