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Table 2 The list of MBLs detected using computational model and shotgun sequence data

From: Sewage effluent from an Indian hospital harbors novel carbapenemases and integron-borne antibiotic resistance genes

Gene name

MBL subclass

Length aa

Closest homolog in NCBI protein database

% identity aa

Accession number

DIM

B1

202

Subclass B1 metallo-beta-lactamase DIM-1 [Pseudomonas stutzeri]

100.0

WP_063860203.1

NDM

B1

248

Metallobetalactamase NDM-1 [Klebsiella pneumoniae]

100.0

AGC54622.1

IMP

B1

240

Beta-lactamase IMP-1 precursor [Pseudomonas aeruginosa]

100.0

CRX26419.1

VIM

B1

248

Subclass B1 metallo-beta-lactamase VIM-2 [Pseudomonadales]

100.0

WP_003108247.1

IMP

B1

240

Subclass B1 metallo-beta-lactamase IMP-15 [Pseudomonas aeruginosa]

100.0

WP_063860575.1

1N26

B1

241

Beta-lactamase [uncultured bacterium]

74.79

ALG03680.1

1N27

B1

242

Subclass B1 metallo-beta-lactamase [bacterium 336/3]

71.97

WP_054042800.1

2N30*

B2

252

ChpA family subclass B2 metallo-beta-lactamase [Aeromonas lacus]

51.48

WP_033113784.1

1N32

B1

241

Hypothetical protein A3D31_07435 [Fluviicola sp. RIFCSPHIGHO2_02_FULL_43_260]

55.04

OGS79779.1

1N4

B1

247

Subclass B1 metallo-beta-lactamase [bacterium 336/3]

73.55

WP_054042800.1

1N59

B1

244

Hypothetical protein A2041_05420 [Bacteroidetes bacterium GWA2_31_9b]

52.7

OFX20903.1

1N6

B1

246

Subclass B1 metallo-beta-lactamase [bacterium 336/3]

59.5

WP_054042800.1

1N8

B1

234

Subclass B1 metallo-beta-lactamase [Flectobacillus major]

70.67

WP_044171073.1

1N9

B1

240

Beta-lactamase [uncultured bacterium]

66.53

ALG03680.1

1N7

B1

273

Hypothetical protein Gferi_08260 [Geosporobacter ferrireducens]

48.0

AOT69571.1

POM-1

B3

223

B3 beta-lactamase [Pseudomonas otitidis]

100.0

ADC79563.1

L-1

B3

210

LW82289.1 metallo-beta-lactamase L1 family protein [Acinetobacter sp. WC-743]

99.52

WP_009585815.1

3N14

B3

283

Subclass B3 metallo-beta-lactamase [Phenylobacterium sp. Root700]

69.58

WP_056733210.1

3N32*

B3

281

BJP_beta_lactamase [uncultured bacterium]

61.59

AIA10847.1

3N33

B3

289

BJP_beta_lactamase [uncultured bacterium]

61.4

AIA10847.1

3N40*

B3

290

Subclass B3 metallo-beta-lactamase [Phenylobacterium sp. Root700]

69.96

WP_056733210.1

3N51*

B3

299

Subclass B3 metallo-beta-lactamase [Novosphingobium sp. PP1Y]C

70.57

WP_013834039.1

3N55*

B3

284

Subclass B3 metallo-beta-lactamase [Phenylobacterium sp. Root700]K

70.82

WP_056733210.1

3N61*

B3

297

Subclass B3 metallo-beta-lactamase [Croceicoccus marinus]

57.65

WP_066847047.1

3N73#

B3

295

BJP_beta_lactamase [uncultured bacterium]

62.98

AIA10847.1

3N8

B3

297

Subclass B3 metallo-beta-lactamase [Sphingomonadaceae]E

55.85

WP_008831296.1

3N1*

B3

300

Subclass B3 metallo-beta-lactamase [Novosphingobium sp. Leaf2]

53.0

WP_056771586.1

  1. *These genes were positive in the CarbaNP test
  2. #This gene was negative in the CarbaNP test