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Table 1 Putative novel resistance genes and gene variants detected in integron gene cassettes

From: Sewage effluent from an Indian hospital harbors novel carbapenemases and integron-borne antibiotic resistance genes

Gene name Length (amino acid) Closest homologue in NCBI protein database Identity (%) Accession number Resistance against
aadA- like-1 288 Aminoglycoside adenyltransferase, partial [Escherichia coli] 89 AEG64741.1 Aminoglycosides
sat-like-1 301 Streptomycin 3-adenylyltransferase [Yersinia pestis biovar Orientalis str. IP275] 94 EDR32758.1 Aminoglycosides
aadA- like-2 287 Aminoglycoside adenyltransferase, partial (plasmid) [Escherichia coli] 94 AIL81899.1 Aminoglycosides
CAT-like 170 Chlor_Acetyltrans_CAT, partial [uncultured bacterium] 92 AMP56890.1 Amphenicols
blaRSA1* 270 Class A extended-spectrum beta-lactamase BEL-1 [Pseudomonas aeruginosa] 53 WP_063857830.1 Beta-lactams
OXA-like-1 300 Class D [uncultured bacterium] 87 AMP47162.1 Beta-lactams
OXA-like-2 266 Class D [uncultured bacterium] 91 AMP48561.1 Beta-lactams
OXA-like-3 266 Oxacillin-hydrolyzing class D beta-lactamase OXA-10 [Gammaproteobacteria] 92 WP_000846390.1 Beta-lactams
OXA-like-4 266 Oxacillin-hydrolyzing class D beta-lactamase OXA-119 [Pseudomonas aeruginosa] 93 WP_032490445.1 Beta-lactams
AmpC-like-1 329 Beta-lactamase [Vibrio cholerae non-O1/non-O139] 94 BAE71359.1 Beta-lactams
OXA-like-5 275 Oxacillin-hydrolyzing class D beta-lactamase OXA-2 [Proteobacteria] 95 WP_001007673.1 Beta-lactams
IMP-like-1 (IMP-81) 246 Subclass B1 metallo-beta-lactamase IMP-15 [Pseudomonas aeruginosa] 96 WP_063860575.1 Beta-lactams
qacE-like-1 110 QacE [uncultured bacterium] 81 ACN22612.1 Disinfectants
qacG-like-1 96 QacG, partial [uncultured bacterium] 90 ACS73614.1 Disinfectants
arr-like-1 150 NAD(+)--rifampin ADP-ribosyltransferase Arr-6 [Pseudomonas aeruginosa] 86 WP_063842214.1 Rifampicin
sul4 # 280 Dihydropteroate synthase [Ardenticatena] 68 CUS02277.2 Sulfonamides
Dfr-like 1 107 Dihydrofolate reductase [Pseudomonas aeruginosa] 88 BAT62904.1 Trimethoprim
Dfr-like 2 157 Dihydrofolate reductase, partial [Vibrio cholerae] 89 AAT37842.1 Trimethoprim
  1. *The sequence is 100% identical to blaRSA1
  2. #The sequence is 100% identical to sul4