Fig. 8

a The Spearman correlation coefficient revealed the association between the changes of fermentation parameters and the expression of these eight growth-related genes (SCC > 0.85 and p < 0.01). The lines’ colour represents two kinds of correlation: blue, negative correction and red, positive correction. b The co-regulation network of these eight genes is related to rumen epithelium growth. The arrow represents the activation of the signalling pathway, and the horizontal line represents the inhibition of the signalling pathway. The signalling pathways and functions involved in the network were predicted by the KEGG pathway analysis. The different colour lines represent different functions that these pathways regulated. Abbreviations: A, B cell receptor signalling pathway; B, Jak-STAT signalling pathway; C, mTOR signalling pathway; D, cGMP-PKG signalling pathway; E, ErbB signalling pathway; F, Ras signalling pathway; G, VEGF signalling pathway; H, thyroid hormone signalling pathway; I, neurotrophin signalling pathway; J, insulin signalling pathway; K, cAMP signalling pathway; L, PI3K-Akt signalling pathway; M, Rap1 signalling pathway; N, prolactin signalling pathway; O, phospholipase D signalling pathway; P, oestrogen signalling pathway; Q, chemokine signalling pathway; R, oxytocin signalling pathway; S, HIF-1 signalling pathway; T, FoxO signalling pathway; U, T cell receptor signalling pathway; V, TNF signalling pathway; W, TGF-beta signalling pathway; X, MAPK signalling pathway; Y, sphingolipid signalling pathway; Z, NF-kappa B signalling pathway; AA, RIG-I-like receptor signalling pathway; AB, hippo signalling pathway