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Fig. 1 | Microbiome

Fig. 1

From: Evolution of the gut microbiome following acute HIV-1 infection

Fig. 1

Microbial genus richness and diversity indices obtained with 16S rRNA gene sequencing. a Median ± IQR values in different cross-sectional comparison groups. Kruskal–Wallis p values are shown at the bottom of each plot. Asterisks (p values *< 0.1 and **< 0.05) highlight statistically significant Tukey post hoc pairwise differences between groups, corrected for multiple comparisons (FDR < 0.05). b, c Linear mixed models of the dynamics of richness and diversity indices in recently HIV-infected (RHI, red) and HIV-negative (NEG, green) subjects over time. Horizontal axes show months after study enrollment. Each dot corresponds to a sample, and samples from the same individual through follow-up are line-connected. Single dots correspond to individuals with no longitudinal follow-up. Thick black lines correspond to the modeled slope of each parameter. Vertical dashed lines show the inflection point at month 6 used for modelling in b and c. Statistically, significant differences from 0 (flat slope) are shown with asterisks. p values *< 0.1 and **< 0.05

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