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Table 1 Overview and properties of 28 L. crispatus strains isolated from vaginal swabs with Lactobacillus-dominated vaginal microbiota or dysbiotic vaginal microbiota

From: Comparative genomics of human Lactobacillus crispatus isolates reveals genes for glycosylation and glycogen degradation: implications for in vivo dominance of the vaginal microbiota

Strain information Clinical information vaginal sample Pan-genome overview
Accession no. ID Group Nugent score VM cluster [4] Urogenital infection Genome size (Mb) GC content No. of core genes No. of accessory genes No. of unique genes
NKLQ00000000 RL03 LVM 0 II None 2.52 36.86 1429 846 12
NKLP00000000 RL05 LVM 0 II None 2.53 36.39 1429 553 243
NKLO00000000 RL06 LVM 0 II None 2.16 36.92 1429 481 11
NKLM00000000 RL08 LVM 0 I None 2.25 36.82 1429 606 43
NKLL00000000 RL09 LVM 0 II None 2.25 36.83 1429 559 21
NKLK00000000 RL10 LVM 0 I None 2.15 36.91 1429 612 31
NKLJ00000000 RL11 LVM 0 II None 2.17 36.90 1429 482 5
NKLF00000000 RL16 LVM 3 II None 2.56 36.49 1429 855 27
NKKX00000000 RL26 LVM 3 II None 2.21 36.90 1429 525 103
NKKW00000000 RL27 LVM 3 I None 2.51 36.84 1429 815 78
NKKU00000000 RL29 LVM 2 II None 2.20 36.88 1429 501 44
NKKR00000000 RL32 LVM 1 II CA 2.34 36.97 1429 644 63
NKLR00000000 RL02 DVM 9 III None 2.22 36.88 1429 528 13
NKLN00000000 RL07 DVM 10 IV None 2.16 36.94 1429 498 6
NKLI00000000 RL13 DVM 9 V None 2.19 36.89 1429 488 28
NKLH00000000 RL14 DVM 9 V None 2.56 36.76 1429 837 63
NKLG00000000 RL15 DVM 8 V CT 2.27 36.79 1429 593 74
NKLE00000000 RL17 DVM 8 III None 2.31 37.08 1429 605 250
NKLD00000000 RL19 DVM 8 V None 2.41 36.93 1429 527 117
NKLC00000000 RL20 DVM 10 III Candida 2.49 36.47 1429 660 41
NKLB00000000 RL21 DVM 9 V None 2.49 36.79 1429 807 72
NKLA00000000 RL23 DVM 10 III None 2.30 36.84 1429 621 1
NKKZ00000000 RL24 DVM 9 III None 2.37 36.72 1429 682 9
NKKY00000000 RL25 DVM 9 V None 2.32 36.84 1429 618 16
NKKV00000000 RL28 DVM 10 IV None 2.17 36.88 1429 489 63
NKKT00000000 RL30 DVM 10 IV None 2.27 36.76 1429 603 20
NKKS00000000 RL31 DVM 10 IV CA 2.31 36.93 1429 652 48
NKKQ00000000 RL33 DVM 8 I† TV 2.37 36.73 1429 631 31
  1. VM vaginal microbiota, LVM Lactobacillus-dominated VM, DVM dysbiotic VM, CT Chlamydia trachomatis, CA Condylomata accuminata, TV Trichomonas vaginalis, VM clusters: I—L. iners, II—L. crispatus, III—G. vaginalis-Sneathia, IV—Sneathia-Lachnospiraceae, V—Sneathia
  2. † This sample clustered together with L. iners-dominated samples, but contained many reads belonging to BV-associated bacteria