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Table 2 Selection, source, and dosage of prebiotic ingredients for dietary supplementation

From: Prebiotic supplementation in frail older people affects specific gut microbiota taxa but not global diversity

Ingredient [Reference] Trial Outcomes Supplier/product code g/mix
Wheat dextrin [43] Intensive care unit patients (~ 65 years)
10–22 g/day × 2–5 weeks
Increase in Firmicutes, butyrate-producing bacteria (Eubacterium hallii, Eubacterium rectale, Roseburia intestinalis, Clostridia cluster XIVa), starch degrading bacteria (Ruminococcus bromii, Ruminococcus obeum, Sporobacter terminitidis), Fecalibacterium prausnitzii, Bifidobacterium spp., & SCFA levels Ingredion/Nutriose FB 06 3
Resistant starch [24] Rats 10%–20 weeks Reduced incidence of colon carcinogenesis possibly through an increase in butyrate Ingredion/Novelose 330 10
Polydextrose [3] Healthy males (20–40 years)
21 g/day × 21 days
Increase in Faecalibacterium, Phascolarctobacterium and Dialister Danisco/Litesse 3
Soluble corn fiber [3] Healthy males (20–40 years)
21 g/day × 21 days
Increase in Faecalibacterium, Phascolarctobacterium, Dialister, Roseburia and Lactobacillus Tate and Lyle/ SCF 22–5421/Promitor soluble fiber 85 3
Galactooligo-saccharide [4] Healthy humans (19–50 years)
5–10 g/day × 16 weeks
Bifidogenic, increase in Fecalibacterium prausnitzii and Actinobacteria and reduction in Bacteroides Friesland Campina/Vivinal GOS 2
Total max daily supplement 21