Skip to main content
Fig. 1 | Microbiome

Fig. 1

From: An integrated meta-omics approach reveals substrates involved in synergistic interactions in a bisphenol A (BPA)-degrading microbial community

Fig. 1

Scheme of the experimental design and analytical pipeline used in this study. Targeted metabolite analysis (green lines) was used to investigate the biodegradation intermediates and dynamics, which were integrated with metagenomic annotation (blue lines) to construct the community-wide BPA-mineralizing pathways. Integrated analyses of 16S-sequencing (light blue lines), metagenomics, and metatranscriptomics (orange lines) identified functionally active populations and metabolic pathways of individual strains in the community. Correlation of individual activities and overall community-wide BPA mineralization revealed the interactions of major community populations (thick red line) which was confirmed by the genomic and metabolite analysis of bacterial isolates from the community (fine blue line and fine red line, respectively)

Back to article page