Fig. 4
From: Host immunoglobulin G selectively identifies pathobionts in pediatric inflammatory bowel diseases
Ratio of IgG+/IgG− binding (ICI) in shotgun metagenomic library patient samples. a The ICI for each species identified was calculated for non-IBD (n = 2), remission/mild CD (CDr/m; n = 2), moderate/severe CD (CDm/s; n = 2), remission/mild UC (UCr/m; n = 1), and moderate/severe UC (UCm/s; n = 2) and is expressed in a cladogram using log2-based heatmap coding. Red boxes highlight species selected for in vitro examination. b Ratio of IgG binding (ICI) for four of the bacterial species of interest in which each dot represents an individual patient, offering further validation