Table 1 Genus-level classification and relative abundances of OTUs found to be significantly indicative (LDA ≥ 2.0, P < 0.05) of time point and clinical outcome by LEfSe analysis. Only the 15 most abundant genera are shown
Family | Genus | Â | Response | Recurrence | |||||
|---|---|---|---|---|---|---|---|---|---|
Donor | Pre-FMT | Days | Weeks | Months | Long-term | Days | Weeks | ||
Bacteroidaceae | Bacteroides | 13.1 ± 3.3 | 2.1 ± 0.4 | 0.5 ± 0.1 | 0.1 ± 0.1 | 2.7 ± 0.3 | 1.9 ± 0.4 | 2.7 ± 0.8 | 1.5 ± 0.5 |
Parabacteroides | 3.2 ± 1.0 | 0.9 ± 0.5 | 0.0 ± 0.0 | 8.5 ± 0.9 | 0.2 ± 0.1 | 0.2 ± 0.1 | 0.1 ± 0.0 | 0.2 ± 0.1 | |
Coriobacteriaceae | Collinsella | 5.7 ± 1.3 | 0.6 ± 0.4 | 0.5 ± 0.1 | 5.0 ± 0.8 | 1.3 ± 0.4 | 2.1 ± 0.5 | 0.9 ± 0.2 | 0.8 ± 0.2 |
Enterobacteriaceae | Esherichia/Shigella | 9.4 ± 1.1 | 0.7 ± 0.2 | 1.0 ± 0.2 | 2.5 ± 0.5 | 2.1 ± 0.3 | 3.2 ± 0.4 | 1.1 ± 0.2 | 1.3 ± 0.1 |
Lachnospiraceae | Anaerostipes | 13.0 ± 1.6 | 0.9 ± 0.4 | 1.3 ± 0.3 | 1.6 ± 0.4 | 2.1 ± 0.3 | 2.6 ± 0.4 | 0.7 ± 0.1 | 1.3 ± 0.2 |
Blautia | 12.3 ± 1.4 | 1.3 ± 0.4 | 1.1 ± 0.2 | 1.8 ± 0.6 | 2.7 ± 0.4 | 2.9 ± 0.4 | 0.7 ± 0.1 | 1.4 ± 0.2 | |
Coprococcus | 3.4 ± 1.8 | 0.5 ± 0.5 | 0.8 ± 0.5 | 10.6 ± 3.4 | 2.0 ± 1.1 | 0.9 ± 0.5 | 0.5 ± 0.2 | 0.7 ± 0.4 | |
Dorea | 7.9 ± 2.1 | 0.0 ± 0.0 | 1.1 ± 0.3 | 5.3 ± 1.5 | 1.8 ± 0.5 | 2.1 ± 0.8 | 0.7 ± 0.2 | 1.0 ± 0.3 | |
Fusicatenibacter | 13.1 ± 3.3 | 2.1 ± 0.4 | 0.5 ± 0.1 | 0.1 ± 0.1 | 2.7 ± 0.3 | 1.9 ± 0.4 | 2.7 ± 0.8 | 1.5 ± 0.5 | |
Moryella | 3.2 ± 1.0 | 0.9 ± 0.5 | 0.0 ± 0.0 | 8.5 ± 0.9 | 0.2 ± 0.1 | 0.2 ± 0.1 | 0.1 ± 0.0 | 0.2 ± 0.1 | |
Roseburia | 5.7 ± 1.3 | 0.6 ± 0.4 | 0.5 ± 0.1 | 5.0 ± 0.8 | 1.3 ± 0.4 | 2.1 ± 0.5 | 0.9 ± 0.2 | 0.8 ± 0.2 | |
Oscillospiraceae | Oscillibacter | 9.4 ± 1.1 | 0.7 ± 0.2 | 1.0 ± 0.2 | 2.5 ± 0.5 | 2.1 ± 0.3 | 3.2 ± 0.4 | 1.1 ± 0.2 | 1.3 ± 0.1 |
Rikenellaceae | Alistipes | 13.0 ± 1.6 | 0.9 ± 0.4 | 1.3 ± 0.3 | 1.6 ± 0.4 | 2.1 ± 0.3 | 2.6 ± 0.4 | 0.7 ± 0.1 | 1.3 ± 0.2 |
Ruminococcaceae | Faecalibacterium | 12.3 ± 1.4 | 1.3 ± 0.4 | 1.1 ± 0.2 | 1.8 ± 0.6 | 2.7 ± 0.4 | 2.9 ± 0.4 | 0.7 ± 0.1 | 1.4 ± 0.2 |
Veillonellaceae | Veillonella | 3.4 ± 1.8 | 0.5 ± 0.5 | 0.8 ± 0.5 | 10.6 ± 3.4 | 2.0 ± 1.1 | 0.9 ± 0.5 | 0.5 ± 0.2 | 0.7 ± 0.4 |