Skip to main content
Fig. 8 | Microbiome

Fig. 8

From: Enterobacteriaceae are essential for the modulation of colitis severity by fungi

Fig. 8

Enterobacteriaceae overgrowth increased fungal fitness during gut colonization. a Experimental design for the administration of colistin and vancomycin antibiotics and fungal gavages in conventional mice without DSS treatment. b Relative (left) and absolute (right) Enterobacteriaceae levels in the fecal microbiota of mice treated for 7 days with colistin, vancomycin, or vehicle (PBS) were quantified using 16S RNA qRT-PCR and were normalized to the vehicle group (PBS), day 0. Data are presented as the mean ± s.e.m. (n = 5 per group). c C. albicans (CA) and S. boulardii (SB) counts in the feces of mice treated with colistin (C), vancomycin (V), or vehicle (PBS) and administered CA and SB by gavage. For statistical comparisons, an asterisk (*) indicates C. albicans + vancomycin versus C. albicans + colistin, and (&) indicates S. boulardii + vancomycin vs. C. albicans + vancomycin (n = 5 per group). d C. albicans levels (left) and S. boulardii levels (right) in the fecal microbiota were quantified using specific qRT-PCR primers and were normalized to the bacterial population (n = 5 per group). Throughout, data are presented as the mean ± s.e.m. *P < 0.05, **P < 0.01, and &&&P < 0.001 by one-way ANOVA with a post hoc Tukey or Dunn’s test

Back to article page