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Fig. 2 | Microbiome

Fig. 2

From: Enterobacteriaceae are essential for the modulation of colitis severity by fungi

Fig. 2

Broad-spectrum ABX protect against DSS-induced colitis, and fungi have limited effects on DSS-induced colitis in their presence. a Experimental design for the administration of broad-spectrum antibiotics (ABX) and dextran sulfate sodium (DSS). b Weight of DSS-exposed mice (n = 12). For statistical comparisons, asterisk (*) indicates ABX versus H2O. c Length of the colons of mice treated with ABX + C. albicans, ABX + S. boulardii, or ABX and H2O on day 12 (n = 12). d Secreted lipocalin (pg/mg of feces) at d0, d7, and d12 after DSS (n = 6). e Representative H&E-stained images of proximal colon cross sections on day 12 after initial DSS exposure. f Histological scores on day 12 (n = 6). Throughout, data are presented as the mean ± s.e.m. *P < 0.05, **P < 0.01, and ***P < 0.001 by one-way ANOVA with a post hoc Tukey test

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