Skip to main content

Table 1 Summary of results

From: The tick endosymbiont Candidatus Midichloria mitochondrii and selenoproteins are essential for the growth of Rickettsia parkeri in the Gulf Coast tick vector

  Parameters Rickettsia parkeri (Rp-) ticks Rickettsia parkeri (Rp+) ticks
Rickettsia parkeri and symbionts dynamics R. parkeri load (Rp) No. R. parkeri Increases load with blood meal in immature ticks.
Decreases load along the blood meal in adult (female) tissues.
Candidatus Midichloria mitochondrii (CMM) Present across the tick life cycle.
Blood meal reduces the abundances.
Proliferates with Rp infections.
Francisella-like endosymbiont (FLE) Present across the tick life cycle.
Blood meal reduces the abundances.
May get displaced with Rp infections.
Total bacterial load (BL) Blood meal reduces the abundances. Increase with Rp infections.
Transcriptional expressions of selenoproteins Midgut tissues SelO and SelS constantly express while SelM is cyclical (gradually peaking up and then decreases). SELENOK, SELENOO, SELENOS, SELENON, and SELENOX upregulated
Salivary glands Spiked at unfed (SelO) and spiked at early feeding and later diminishes (SelS) while SelM cyclical. eEFSec, SELENOM, SELENOK, SELENOS, TrxR, and GST upregulated
Ovarian tissues nd SELENOM and SELENOO upregulated
Knockdown of selenoproteins ΔSelM SG: depleted Rp, BL, and FLE
ΔSelO MG: depleted Rp, BL, and CMM
ΔSelS MG: depleted BL, FLE
SG: depleted CMM
  1. Knockdown of SELENOM or SELENOO or SELENOS by RNAi method. Nd: not determined across the blood meal
  2. MG midguts, SG salivary glands, Rp Rickettsia parkeri, CMM Candidatus Midichloria mitochondrii, FLE Francisella-like endosymbionts, ΔSelM or SelO or SelS