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Fig. 4 | Microbiome

Fig. 4

From: A metagenomic study of the gut microbiome in Behcet’s disease

Fig. 4

Effect of transplantation of feces from BD patients on EAU. Pooled feces from active BD patients transferred to B10RIII mice by oral gavage. Pooled feces from healthy individuals and PBS were transferred to mice as control groups. EAU was induced by immunization with IRBP161–180. On day 14 after EAU induction, clinical and histological scores of BD patients’ feces-treated group (a and d), healthy’ feces-treated group (b and e), and PBS-treated group (c and f) were determined. Combined data in (g) for clinical score and (h) for histological score. Each point represents an individual eye. The horizontal bars denote the average scores of each group. The spleens were also removed from EAU mice on day 14 after induction. IFN-γ (i) and IL-17 (j) mRNA levels were evaluated by real-time PCR

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