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Fig. 2 | Microbiome

Fig. 2

From: Disruption of maternal gut microbiota during gestation alters offspring microbiota and immunity

Fig. 2

Maternal gut microbiota indirectly impacts genital tract and breastmilk microbiota. a Experimental setup: BALB/c mice were treated with vancomycin 5 days prior to delivery (Mg) or left untreated (Mc). Four days after delivery, mice were sacrificed and genital tract samples collected for 16S rRNA gene analysis. Stomach contents were also collected from pups’ stomach for microbiome analysis. b Shannon index of Mg (blue) versus Mc (red) genital tract microbiota. c Shannon index of stomach contents microbiota (collected from pups’ stomach 4 days after delivery). d Principal coordinate analysis of stomach contents microbiota day 4 postpartum by Bray-Curtis dissimilarity. e Shannon index of stomach contents microbiota collected from pups’ stomachs 14 days after delivery. f Principal coordinate analysis of stomach contents microbiota by Bray-Curtis dissimilarity collected 14 days after delivery. g Bayesian estimates of the proportion of microbes in pup stool that came from the mother. Error bars represent standard error of the mean (SEM). Data representative of two independent experiments. n = 4–6 breastmilk/2 genital tract samples per group per experiment. *p < 0.05

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