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Fig. 1 | Microbiome

Fig. 1

From: Probiotic Bifidobacterium strains and galactooligosaccharides improve intestinal barrier function in obese adults but show no synergism when used together as synbiotics

Fig. 1

Experimental design and participant flow diagram. a Time line for the human trial. Four visits were required from each subject. At visit 1, potential subjects were screened for eligibility and provided with a 3-day food record, all supplies for stool and urine collection (stool kit, urine collection containers, sugar cocktail, and aspirin), and instructions for specimen handling and for completing these tasks before the next visit. Each subject collected stool before taking the sugar cocktail to avoid potential effects of sugar cocktail on microbiota composition. Details of the stool and urine collection are shown. GSSC, Gastrointestinal Symptom and Severity Checklist. b Participant flow diagram showing the progress through the phases of the randomized controlled trial (enrollment, intervention allocation, follow-up, and data analysis)

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