Fig. 2

Principal coordinate analysis (PCoA) of generalized UniFrac distances. Each dot represents a sample and each color indicates a body site: stool (blue), skin upper body (green), skin lower body (red), and oral cavity (purple). The distribution of samples by body site is shown along the first and second axes of the PCoA plot. Along the first axis (PC1), the sample distribution differed significantly between the stool and skin upper body (p = 0.0048), the stool and oral cavity (p < 0.0001), skin upper body and skin lower body (p = 0.0049), skin upper body and oral cavity (p = 0.0049), and skin-lower body and oral cavity (p < 0.0001), but not between the stool and skin lower body (p = 0.1842; p values determined by pairwise Wilcoxon rank sum tests with Benjamini-Hochberg correction). Along the second axis (PC2), the oral samples differed from the skin upper body (p < 0.0001) and skin lower body (p < 0.0001), but other sites were not significantly different