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Table 4 Summary of the statistics from the time-course analysis of the fecal microbiota during the immunization protocol (T0–T4) and between immunizations (βgal and TSHR)

From: Gut microbiota in experimental murine model of Graves’ orbitopathy established in different environments may modulate clinical presentation of disease

Index

ANOVA model

TSHR vs. βgal group

Immunization

Time

Time × immunization

T0

T1

T2

T3

T4

Chao

0.006

0.02

0.8

0.75

0.066

0.28

0.33

0.027

Shannon

0.054

0.28

0.47

0.44

0.023

0.35

0.35

0.29

Firm:Bact

0.406

0.0003

0.16

0.39

0.028

0.46

0.2

0.26

  1. Firm:Bact, Firmicutes/Bacteroidetes ratio. ANOVA model as previously described. Pairwise comparison between βgal and TSHR in each time point has been made with a pairwise T-test with Benjamini-Hochberg correction for FDR