Gut microbiota in experimental murine model of Graves’ orbitopathy established in different environments may modulate clinical presentation of disease

Table 3 Traditional microbiology results from TSHR-immunized mouse intestinal scraping from Center 1 (n = 5) and Center 2 (n = 10)

Microbial target	Center 1: mean counts	Center 2: mean counts	P values
Bacteroides	1.15E+05	b.d.l.	0.000
Bifidobacteria	6.41E+06	1.32E+06	0.057
Coliforms	3.27E+02	1.15E+03	0.453
E.coli	b.d.l.	8.45E+02	0.499
Enterobacteria	b.d.l.	6.82E+02	0.499
Enterococci	1.74E+05	6.10E+06	0.247
Lactobacilli	1.93E+06	4.68E+06	0.725
Staphylococci	1.31E+05	3.77E+05	0.175
Total aerobes	4.18E+05	9.90E+06	0.370
Total anaerobes	6.75E+06	7.39E+05	0.001
Total Clostridia	2.46E+04	b.d.l.	0.165
Yeast	8.72E+01	b.d.l.	0.031

b.d.l.: below detection limit. Detection limits are the following according to the agar used: 1000 CFU/g feces for Bacteroides, 100 CFU/g feces for E.coli and coliforms as well as for enterobacteria, and 10 CFU/g feces for total clostridia and yeasts, respectively. Microbiological counts were Box-Cox transformed. P values obtained by linear regression

ISSN: 2049-2618