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Fig. 2 | Microbiome

Fig. 2

From: Metabolic retroconversion of trimethylamine N-oxide and the gut microbiota

Fig. 2

Effect of TMAO on mixed faecal microbial population in vitro. a Enumeration of selected bacteria in fermentation vessels by FISH analysis. Red lines, TMAO-containing systems; blue lines, negative controls. Data are shown as mean + SD (n = 3). Eub338, total bacteria; Ent, Enterobacteriaceae; Bif164, Bifidobacterium spp.; Lab158, lactic acid bacteria. *Statistically significantly different (adjusted P < 0.05) from the control at the same time point. Full data are shown in Additional file 1: Figure S1. b 1H-NMR data for batch culture samples. Data are shown as mean ± SD (n = 3). Red lines, TMAO-containing systems; blue lines, negative controls. *Statistically significantly different (P < 0.05) from the negative control at the same time point. c Bidirectional clustering of correlation matrix of FISH data and data for the six metabolites found in the highest amounts in the NMR spectra from the batch-culture samples. +Adjusted P value (Benjamini–Hochberg) statistically significant (P < 0.05). FISH and metabolite data and a table of correlations and adjusted P values (Benjamini–Hochberg) for the batch-culture samples are available in Additional file 1: Table S3–S5

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