Fig. 2

Phylogenetic shifts in the core salivary microbiome during various dentition states. a The salivary core microbiome (present in at least 75% of individuals in the group) of children in predentate, primary, mixed, and adult dentitions, as well as those of unrelated adults. Each bar represents presence of species. Data for a is presented in Additional file 4: Table S2. Shannon diversity index is shown in Fig. b and equitability in Fig. c. The distribution of species by gram staining characteristics and oxygen requirements in each dentition state is shown in Fig. d. Probable gram staining characteristics and oxygen requirements were attributed to uncultivated species based on phylogenetic relatedness to the closest cultivated species. In all the figures, groups that share the same symbol are significantly different from each other (p < 0.05, Dunn’s test). The similarity between children in different dentition states and their biological mother is shown in e. Groups that are bracketed are significantly different from each other (p < 0.05, Dunn’s test)