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Fig. 4 | Microbiome

Fig. 4

From: Gut-dependent microbial translocation induces inflammation and cardiovascular events after ST-elevation myocardial infarction

Fig. 4

Schematic diagrams showing the coefficients relating inflammation markers, compromised LVEF with adverse cardiovascular events and the mediation effect of translocation z-score. a Association between CD14++CD16+ monocytes and MACE mediated by translocation z-score. b Association between compromised LVEF (derived from Youden index for MACE) and MACE mediated by translocation z-score. c Association between hs-CRP and MACE mediated by translocation z-score. β indicates coefficients in regression analysis; TE, total effect; ADE, average direct effect; ACME, average causal mediation effect; CI, confidence interval; MACE, major adverse cardiovascular events; LVEF, left ventricular ejection fraction; hs-CRP, high-sensitivity C-reactive protein. *P < 0.05, **P < 0.01

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