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Table 1 Concentrations of hydrogen peroxide and lactic acid produced by Lactobacillus spp. under different conditions and concentrations necessary to inactivate HIV and BV-associated bacteria

From: The implausible “in vivo” role of hydrogen peroxide as an antimicrobial factor produced by vaginal microbiota

Conditions H2O2 [mM]   Lactic acid [mM]  
Culture medium under hypoxic conditions Undetectable [46] 160–250 [22, 47]
Aerated culture medium 3.34–4.39 [46] 45 [22]
Lactobacillus-dominated CVF under hypoxic conditions Undetectable [16] 110 [23]
Aerated Lactobacillus-dominated CVF 0.023 [16] 63 [23]
Inactivation of HIV in culture medium 5 [48] 33 [32]
Inactivation of BV-associated bacteria in culture medium 10 [23] 55–110 [23]
Inactivation of HIV in the presence of CVF Undetermined   33–110 [32]
Inactivation of BV-associated bacteria in the presence of CVF > 1000 [23] 55–110 [23]
Inactivation of Lactobacillus in culture medium > 1000 [23] > 1000 [23]