Fig. 4

Multi-omic profiling provides an overview of the different -omics and models of the interactions between host and pathogens. Using our in-house narrowed-down database, Brenneria goodwinii was found to be the most active bacterium and the primary pathogenic agent in the AOD lesion microbiome based on metatranscriptomics and metaproteomics (depicted as Bg and yellow colour in the figure). Gibbsiella quercinecans (Gq and white colour in the figure) and Rahnella victoriana (Rv and blue colour in the figure) were found to provide some ambiguous activity. Other Gram-negative species (collectively called G−, with grey colour in the figure) and two predicted Gram-positive bacterial genomes (collectively called G+ in the figure and coloured red) provided some virulent activity as well. The size of each bacterial species/group indicates their relative abundance in each dataset (not to scale). The colour of active groups of virulence-associated genes of interest are coloured coded as their associated bacterial origin. Active plant proteins and genes are coloured dark green. The depicted shapes correspond to different virulence-associated functions