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Table 1 Descriptive characteristics of the study samples (n = 75)

From: Haemophilus is overrepresented in the nasopharynx of infants hospitalized with RSV infection and associated with increased viral load and enhanced mucosal CXCL8 responses

No. of participants (n = 75) Control Mild Moderate Severe Recovery
n = 21 n = 9 n = 27 n = 18 n = 25
Age (days) 89 (37) 88 (29) 75 (50) 37 (21) 109 (48)
Hospital Stay (days) 0 (0) 3 (3) 8 (5) 14 (6) 0 (0)
RSV viral load (Ct) 50.0 (0) 22.4 (3.3) 27.0 (5.4) 23.6 (3.4) 50.0 (0)
Weight (gram) N/A N/A 14,674 (21111) 5516 (2002) 3874 (931) 5375 (2333)
Birth weight (gram) 2624 (768) 3323 (618) 3271 (656) 2867 (738) 3116 (677)
% antibiotics 0%   22%   7%   11%   8%  
% breastfed 38%   67%   56%   72%   76%  
% males 24%   56%   52%   44%   44%  
Mean number of reads 27,449 (4464) 24,916 (4826) 21,787 (5776) 28,866 (32974) 22,658 (5208)
Total number of reads 5.76E+05   2.24E+05   5.88E+05   5.20E+05   5.66E+05  
 Assigned at family 99.72% (0.01%) 99.88% (0.01%) 99.90% (0.01%) 99.94% (0.01%) 99.91% (0.01%)
 Assigned at genus 94.72% (0.07%) 97.91% (0.03%) 98.98% (0.02%) 98.15% (0.03%) 97.89% (0.04%)
 Assigned at speciesa 21.22% (0.19%) 8.07% (0.06%) 10.25% (0.09%) 10.27% (0.09%) 8.43% (0.17%)
Mean number of OTUs 203 (56) 167 (44) 139 (38) 150 (38) 160 (50)
Total number of OTUs 4270   1499   3756   2705   3999  
Mean Chao indexb 176.8 (54.4) 151.7 (42.6) 131.1 (39.4) 137.5 (17.8) 150.2 (53.5)
Mean Shannon indexb 3.1 (1.1) 2.8 (0.7) 2.4 (0.8) 2.7 (0.7) 2.4 (0.8)
Mean PDWT indexb 6.0 (1.7) 5.6 (1.1) 5.1 (1.6) 4.9 (0.9) 6.1 (2.0)
  1. Data are presented as average + standard deviation (SD) for continuous variables and as percentages for categorical variables. Numbers listed in brackets: SD. The antibiotic use was at the time of infection, and breastfeeding duration was not specified
  2. aNote that due to technical limitations in the resolution of 16S marker gene sequencing, OTU (Operational Taxonomic Unit) calling on the level of species should be interpreted with caution
  3. bAlpha diversity metrics