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Table 1 Demographics of the lung microbiome cohort. Values presented as mean (SD) except for those that are the percentage of the subset denoted with (%). P values are from Welch t tests for continuous variables and from Fisher’s exact tests for percentages

From: Fungi stabilize connectivity in the lung and skin microbial ecosystems

  Cohort HIV+ HIV− p-value COPD+ COPD− p value
N 25 14 11 13 12
Age (years) 51.5 (7.7) 51.2 (8.3) 51.9 (7.4) 0.8472 49.4 (8.1) 53.6 (7.1) 0.2032
Male (%) 88.0 92.9 81.8 0.5648 92.3 83.3 0.5930
White (%) 56.0 50.0 63.6 0.6887 53.8 58.3 1.0000
Current smokers (%) 20.0 28.6 9.1 0.4913* 30.8 8.3 0.4671*
Former smokers (%) 12.0 14.3 9.1   7.7 16.7  
BMI (kg/m2) 25.9 (5.3) 24.2 (4.2) 28.1 (5.9) 0.0792 24.4 (5.4) 27.6 (4.8) 0.1426
Viral load (IU/mL) 1477 (2850) 2053.5 (3230.5; N = 10) 35.5 (18.2; N = 4) 0.0746
CD4 count (cells/mm3) 646 (305) 620.2 (326.2; N = 10) 701.8 (278.8; N = 4) 0.6195
FEV1/FVC (%) 79.0 (11.5) 80.1 (8.8) 77.7 (14.6) 0.6435 75.8 (15.0) 82.5 (4.1) 0.1463
DLCO (ml/min/mmHg) 77.2 (15.3) 73.3 (16.0) 82.1 (13.5) 0.1520 66.8 (13.9) 88.4 (6.0) < 0.0001
  1. *Smoking status p value calculated using an ANOVA test