Table 1 Demographics of the lung microbiome cohort. Values presented as mean (SD) except for those that are the percentage of the subset denoted with (%). P values are from Welch t tests for continuous variables and from Fisher’s exact tests for percentages
From: Fungi stabilize connectivity in the lung and skin microbial ecosystems
Cohort | HIV+ | HIV− | p-value | COPD+ | COPD− | p value | |
|---|---|---|---|---|---|---|---|
N | 25 | 14 | 11 | – | 13 | 12 | – |
Age (years) | 51.5 (7.7) | 51.2 (8.3) | 51.9 (7.4) | 0.8472 | 49.4 (8.1) | 53.6 (7.1) | 0.2032 |
Male (%) | 88.0 | 92.9 | 81.8 | 0.5648 | 92.3 | 83.3 | 0.5930 |
White (%) | 56.0 | 50.0 | 63.6 | 0.6887 | 53.8 | 58.3 | 1.0000 |
Current smokers (%) | 20.0 | 28.6 | 9.1 | 0.4913* | 30.8 | 8.3 | 0.4671* |
Former smokers (%) | 12.0 | 14.3 | 9.1 | 7.7 | 16.7 | ||
BMI (kg/m2) | 25.9 (5.3) | 24.2 (4.2) | 28.1 (5.9) | 0.0792 | 24.4 (5.4) | 27.6 (4.8) | 0.1426 |
Viral load (IU/mL) | – | 1477 (2850) | – | – | 2053.5 (3230.5; N = 10) | 35.5 (18.2; N = 4) | 0.0746 |
CD4 count (cells/mm3) | – | 646 (305) | – | – | 620.2 (326.2; N = 10) | 701.8 (278.8; N = 4) | 0.6195 |
FEV1/FVC (%) | 79.0 (11.5) | 80.1 (8.8) | 77.7 (14.6) | 0.6435 | 75.8 (15.0) | 82.5 (4.1) | 0.1463 |
DLCO (ml/min/mmHg) | 77.2 (15.3) | 73.3 (16.0) | 82.1 (13.5) | 0.1520 | 66.8 (13.9) | 88.4 (6.0) | < 0.0001 |