Table 3 Sequencing statistics, median (range). Medians with different letters were significantly different (Tukey P < 0.05). All models included sample type as a random effect

39.9 (14.2–55.3)^a

38.8 (14.1–53.4)^a

346 (322–380)^a

35.0 (34.6–36.1)^ac

43.5 (33.3–65.4)^bd

42.0 (31.0–62.7)^bd

315 (301–343)^bd

34.8 (34.2–35.0)^bd

65.4 (54.7–79.1)^c

64.0 (53.3–77.7)^c

179 (146–186)^c

35.1 (35.0–35.4)^ac

49.1 (27.6–57.7)^bd

46.9 (24.5–55.2)^bd

328 (315–353)^bd

34.6 (33.9–35.0)^bd