Fig. 1

Abundance distribution of microbiome across four mice samples. a Abundance distribution of 17 predefined bacterial taxa for all four mouse genotype/diet groups (Plin2-HF, WT-HF, Plin2-LF, and WT-LF). Blue asterisks indicate the significant shifts in taxon abundance in comparisons of both Plin2 and WT mice fed different diets (p value < 0.05). b–d Venn diagrams of number of mapped microbial transcripts for four samples, Plin2-HF (red), WT-HF (green), Plin2-LF (blue), and WT-LF (yellow) with different cutoffs: b RPKM > 0, c RPKM ≥ 10, and d RPKM ≥ 100