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Fig. 4 | Microbiome

Fig. 4

From: Community characteristics of the gut microbiomes of competitive cyclists

Fig. 4

Characterization of Methanobrevibacter smithii transcriptional activity. a A box plot demonstrating the ratio of mRNA abundance to DNA abundance showed higher transcriptional activity by M. smithii in professional cyclists vs. CAT 1 cyclists (***p < 0.01). b This increased activity by M. smithii directly correlated to six upregulated KEGG pathways, including methane metabolism (p < 0.001). c RNA-Seq reads from seven professional cyclists with high M. smithii activity were mapped to the genome of reference strain M. smithii ATCC 35061. The top 50 most highly expressed genes, as determined by TPM, are presented in a heat map with clustering of genes determined using the BC distance metric. The color strip indicates whether the gene is involved in methane metabolism (blue) or is involved in a separate KEGG pathway (gray)

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