Fig. 2

Characterisation of the gut microbiome between infants diagnosed with late onset sepsis (LOS) and matched controls. a Transition network analysis showing PGCTs in PreLOS samples compared to matched controls approximated as a Markov chain with subject-independent transition probabilities. Arrow weights reflect the transition probabilities from one sample to the next. Size of circle reflects the relative number of samples associated with that PGCT. Pale blue indicates PGCTs of consisting of control samples only, and the darker shade of purple shows increased number of PreLOS samples in that PGCT. b Temporal change in PGCTs in each individual infant. Red lines represent day of LOS diagnosis. Only samples up to day 50 of life are included. Infant 178 died during the study