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Table 1 Demographics and clinical parameters of study subjects

From: The metabolic footprint of the airway bacterial community in cystic fibrosis

Parameter(s)

CF (n = 16)

Control (n = 8)

P value

Age, years

31.0 (25.5, 36.0)

33.5 (26.5, 46.5)

NS*

Sex (male:female)

10:6

0:8

0.006†

Race (EA:AA:other)

15:1:0

1:7:0

0.001†

Antibiotic use (yes:no)

14:2

0:8

NA§

Serum IgE, U/mL

77.5 (29.5, 119.5)

72.5 (23.0, 201.0)

NS

Absolute blood eosinophils

0.16 (0.11, 0.26)

0.11 (0.06, 0.18)

NS

FVC, % predicted

84.0 (59.5, 98.5)

108.0 (99.0, 113.5)

0.003

FEV1, % predicted

72.5 (55.5, 87.5)

106.0 (95.5, 112.0)

0.001

Neutrophils, % of total WBC

71.5 (63.0, 76.0)

58.5 (49.0, 62.5)

0.007

Absolute blood neutrophils

6.29 (3.77, 8.73)

2.77 (1.89, 4.22)

0.005

CF genotype (for full details, see Additional file 1)

 Processing defect (F508del homo/heterozygous)

11

ND⌘

NA

 Gating mutation (G551D)

3

ND

NA

 Non-sense mutation (R1158X, G542X)

2

ND

NA

  1. Proportions are shown as median (IQR). P values were generated from Wilcoxon-Mann-Whitney rank sum test unless otherwise stated
  2. *Not significant
  3. † P value by Fisher’s exact test
  4. §Not applicable
  5. ⌘Not determined