Table 1 Experimental design: pilot experiment. C57BL/6 wild-type (C57BL/6) or congenic C57BL/6 IL-10-deficient (C57BL/6 IL-10−/−) mice with humanized (Hu) or conventional (Conv) microbiota were inoculated with TSB, C. jejuni 260.94, or C. jejuni 11168 and subjected to sterile (Ster.) or specific pathogen-free (SPF) handling for the duration of the experiment; 5 weeks post-inoculation
Group | Handling | Genotype | Microbiota | Inoculum | # of mice |
|---|---|---|---|---|---|
Hu-TSB (Ster.) | Sterile | C57BL/6 | Humanized | TSB | 10 |
Hu-TSB (SPF) | SPF | C57BL/6 | Humanized | TSB | 10 |
Hu-260.94 | Sterile | C57BL/6 | Humanized | 260.94 | 10 |
Hu-11168 | Sterile | C57BL/6 | Humanized | 11168 | 10 |
Conv-11168 | SPF | C57BL/6 | Conventional | 11168 | 10 |
Conv-IL-10−/−11168 | SPF | C57BL/6 IL-10−/− | Conventional | 11168 | 10 |