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Fig. 5 | Microbiome

Fig. 5

From: VirFinder: a novel k-mer based tool for identifying viral sequences from assembled metagenomic data

Fig. 5

Evaluation of VirFinder (VF) and VirSorter (VS) predictions on contigs for 3 length ranges assembled from 20 M reads simulated human gut metagenomes at 50% viral level. Bars depict true prediction rates (TPRs) for VirSorter category I; I and II; and I, II, and III predictions. As in Fig. 2, VirFinder predictions were evaluated at the same false positive rates (FPR) as corresponding VirSorter results. Thirty replicate bootstrap samples of contigs assembled from simulated metagenomes were tested for each condition. Metagenomes were simulated based on the relative abundance of complete virus and host genomes found in a real human gut metagenome. The horizontal bar displays the median, boxes display the first and third quartiles, and whiskers depict minimum and maximum values. Asterisk indicates VirFinder’s TPRs are significantly larger than VirSorter’s (Wilcoxon signed-rank one-sided test, p < 10−4)

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