Fig. 1
From: How holobionts get sick—toward a unifying scheme of disease
What is a good microbiome? A typical example of the tripartite interaction between a common virus, the host, and the microbiota. a Some strains of the influenza virus cause more severe disease in obese persons or mice as well as in third-trimester pregnant woman. This occurrence correlates with a disturbed gut microbiota. b In addition, suboptimal responses to the flu vaccine are found in these populations