Fig. 5

Heat map of discriminant genera determined by LEfSe analysis. a All taxa that were discriminant features in at least one treatment (LDA score >2) are shown, with phylogenetic class reported as colored boxes. Relative abundance is shown scaled by relative abundance within a genus, with a legend provided in the top left. A bar chart at the top of the heat map displays Lipocalin-2 concentrations in individual samples, colored by treatment. All genera are discriminant features relative to the control, while some are discriminant features relative to all treatment groups as denoted by asterisks. b The relative abundance of a single OTU representative from Alistipes, S24-7, Akkermansia, and Lactobacillus within each treatment were graphed by treatment with median and standard deviation shown