Fig. 1

Body weight gain, adipose tissue weight, and adipose tissue histology. a Body weight gain of Sv129 and BL mice fed low-fat (LF), high-fat (HF), or HF + indomethacin (HFI) diets. b, c Tissue weights of epididymal (eWAT), inguinal (iWAT), retroperitoneal (rWAT), and interscapular brown (iBAT) adipose depots in b Sv129 and c BL mice fed low-fat (LF), high-fat (HF), or HF + indomethacin (HFI) diets. Error bars represent s.e.m.. Shared letters on the bars indicate P ≥ 0.05, whereas different letters denote significant differences between the groups (<0.05), Kruskal-Wallis with Dunns post hoc test. d Cumulative feed intake. e Energy efficiency. f Hematoxylin/eosin staining of iWAT tissues from Sv129 and BL mice fed LF, HF or HFI diets. Scale bar = 50 μm