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Fig. 5 | Microbiome

Fig. 5

From: Reduced microbial diversity in adult survivors of childhood acute lymphoblastic leukemia and microbial associations with increased immune activation

Fig. 5

Systemic inflammatory markers are associated with variation in microbial communities. The levels of both systemic inflammatory markers plasma IL-6 and CRP were higher in the survivors than in controls (a, b). Microbial community in the survivors was reduced with Faecalibacterium but enriched for Peptinophilus (c, d). Both IL-6 and CRP were negatively associated with Faecalibacterium and Ruminococcus, while positively associated with Peptoniphilus (e, f). Data shown as median ± interquartile range and p values was calculated with Mann-Whitney test for group comparison. Data shown as correlation coefficient (ρ) and confounders-adjusted p value calculated with Spearman rank partial correlation test adjusted for age, gender and BMI for the correlation between taxa and immune markers. Linear regression line was fitted for visualization purposes only. Red circles denote survivors, while blue squares denote controls. g_ = genus

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Microbiome

ISSN: 2049-2618

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