Fig. 1
From: Normalization and microbial differential abundance strategies depend upon data characteristics
Normalization is critical to result interpretation. a The forensic study matching subject’s fingers to the keyboards they touched (Fierer et al.), rarefied at 500 sequences per sample. b, c Data not normalized, with a random half of the samples subsampled to 500 sequences per sample and the other half to 50 sequences per sample. b Colored by subject_ID. c Colored by sequences per sample. Nonparametric ANOVA (PERMANOVA) R 2 roughly represents the percent variance that can be explained by the given variable. Asterisk (*) indicates significance at p < 0.01. The distance metric of unweighted UniFrac was used for all panels