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Fig. 4 | Microbiome

Fig. 4

From: Sputum DNA sequencing in cystic fibrosis: non-invasive access to the lung microbiome and to pathogen details

Fig. 4

Prediction of antibiotic resistances and other phenotypes. a The Achromobacter strain isolated from patient CF-85 underwent routine clinical testing for antibiotic sensitivity; the compounds tested and the observed results are shown. This is contrasted with automated predictions based on the gene content of the sputum sequence data. b Summary table for all CF subjects, indicating the overlap between the resistance predictions and the clinical test results. c Read alignment against a section of the mucA gene from P. aeruginosa, from patient CF-82. Eleven reads show a wild-type sequence at this position, but 7 reads show a deletion event predicting a non-functional protein and a corresponding shift from a non-mucoid to a mucoid phenotype in this strain

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