Fig. 3From: Revised computational metagenomic processing uncovers hidden and biologically meaningful functional variation in the human microbiomeGrouping gene families into KEGG pathway-based aggregates decreases functional variability. Shown are boxplots of the distributions of coefficient of variation (CoV) values in the abundance of different gene family aggregates across gut metagenomic samples from the Human Microbiome Project. Genome co-occurrence-based aggregates (red) show significantly higher values of CoV compared to KEGG pathway-based aggregates (cyan; P < 10−23, Wilcoxon rank-sum test)Back to article page