Fig. 2
From: Resistant starch can improve insulin sensitivity independently of the gut microbiota
Resistant starches improved insulin sensitivity in C3H mice in the presence of a microbiota. Glycemic response after insulin injection in conventionalized 15-week-old C3H/HeN (C3H) mice fed experimental diets for 7 weeks (a, b) (LFD low-fat diet, WD Western diet, RS2 WD with resistant starch 2, RS4 WD with resistant starch 4). Body weights at necropsy (c), body weight gain over 8 weeks of dietary intervention (d), subcutaneous adipose tissue (SAT) weights at necropsy (e), and energy intake (as recorded over a week at week 4) (f) in conventionalized C3H mice fed experimental diets for 8 weeks. *p < 0.05, **p < 0.01, ***p < 0.001 versus WD (one-way ANOVA with Dunnett’s post hoc tests). Mean ± SEM. a, b N = 6–9. c–e N = 8–9. f N = 4 cages