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Fig. 5 | Microbiome

Fig. 5

From: Distinguishing potential bacteria-tumor associations from contamination in a secondary data analysis of public cancer genome sequence data

Fig. 5

The log10-transformed ratios of bacterial read pairs from a specific taxon to the total number of bacterial read pairs from that patient were calculated for all ovarian cancer patients. These comparisons include counts of Mycobacterium (M), Acinetobacter (A), Pseudomonas (Ps), Staphylococcus epidermidis (S), Ralstonia (R), and Propionibacterium (P) read pairs and the total (T) number of bacterial read pairs from that patient. For example, A/T is the log10-transformed ratio of the number of Acinetobacter-like read pairs divided by the number of total bacteria-like read pairs. The black horizontal line represents the average of the log10-transformed ratios, after excluding those samples lacking data. The patients are color-coded by sample type (a) and by sequencing center (b). The number of samples from each sequencing center is denoted (b). Ratios where the numerator was 0 were assigned an arbitrary value of −7, ratios where both the numerator and denominator were 0 were assigned an arbitrary value of 0, and comparisons where the denominator was 0 were assigned an arbitrary value of 7. Counts for the number of patients where one of these arbitrary values were assigned are shown below the x-axis and are broken down by sequencing center when the sequencing center denotes the color (b). When >5 points are at a given value, some data points may overlap each other making it impossible for all data points to be seen

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