Fig. 1
From: The gut microbiota in conventional and serrated precursors of colorectal cancer
α-Diversity and community types of colonoscopy-screened participants. a Violin plots of species richness and b Shannon diversity index by polyp histology (controls n = 322, CA cases n = 144, HP cases n = 40, SSA cases n = 33), location (distal CA n = 55, proximal CA n = 87), and advancement level (non-advanced CA n = 121, advanced CA n = 22). These indices were calculated for 500 iterations of rarefied (4000 sequences per sample) OTU tables, and the average over the iterations was taken for each participant (1 control excluded due to sequencing depth = 2088). p values from multiple linear regression are shown. c Fitting to the DMM [24, 56] model indicates optimal classification into 5 community types. d Principal coordinate analysis of Jensen-Shannon divergence values between participants, colored by community type. Green community type 1, blue type 2, purple type 3, yellow type 4, red type 5. e Distribution of the community types in groups distinguished by histology, f location, or g advancement level. p value from Fisher’s exact test with Monte Carlo simulation is shown. CAs conventional adenomas, HPs hyperplastic polyps, SSAs sessile serrated adenomas