Fig. 4

Distinct succession of bacteria as a function of diet and maturity. a Mean class level microbiota relative abundance in VLBW and ELBW infants by nutritional group and adjusted gestational age. b Linear mixed-effects (LME) modeled relative abundance and statistical analyses of the four most common types of bacteria identified: Bacillales, Lactobacillales, Clostridiales, and Enterobacteriales reported by nutritional group and adjusted gestational age [>3 weeks postnatal age, >7 days post antibiotics samples only plotted; 86 samples]. Individual infant trajectories (lines) for each infant are plotted along with box and whiskers for LME-modeled relative abundance values. FDR-adjusted p values from the LME models are noted