Staphylococcal species heterogeneity in the nasal microbiome following antibiotic prophylaxis revealed by tuf gene deep sequencing

Table 3 The beta diversity of the nasal staphylococcal microbiome between admission and other sample days after administration of antibiotic surgical prophylaxis in individual study patients, measured by the Bray Curtis dissimilarity distance

Antibiotic surgical prophylaxis received	Patient study ID	Beta diversity (Bray Curtis dissimilarity) Sample day
Antibiotic surgical prophylaxis received	Patient study ID	2	3	4	5	6	7
No antibiotics	25	0.24	0.42	#	0.29
	99	0.12	0.04	0.09
	101	0.55	0.35	0.54
	105	0.01	0.09	0.02	0.37
	111	0.53	0.09	0.06	0.35
	113	0.06	0.20
Flucloxacillin (1 g) and gentamicin (160 mg)	34	0.23	0.21	0.20	0.20	0.21	#
	36	0.35	0.10	0.11	0.13	0.14	0.41
	42	0.25	0.19	0.66	0.33	0.70	0.54
	51	0.42	0.25	0.34
	56	0.03	0.11	0.07	0.26	#	0.17
	61	0.77	0.60	0.65	0.78
Teicoplanin (400 mg) +/− gentamicin (160 mg)	35^b	0.21	0.33	0.33	0.24	#	0.17
	37^b	0.30	0.06	0.22	0.32	0.40	0.20
	65^a	0.08	0.08	0.06
	86^b	0.10	0.18	0.23
	90^a	0.06	0.08	0.05	0.36
	93^a	0.36	0.49	0.29

^aTeicoplanin alone
^bTeicoplanin and gentamicin
^#Beta diversity was not calculated for sample as excluded due to insufficient read depth (<1100)

ISSN: 2049-2618