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Fig. 6 | Microbiome

Fig. 6

From: The impact of sequence database choice on metaproteomic results in gut microbiota studies

Fig. 6

Functional annotation of human and mouse gut metaproteomic data obtained using different databases. DBs were made up of reads (dark blue, R-A) or contigs (red, C-A) from gut metagenomes of all subjects analyzed for each host species, or all bacterial sequences deposited in UniProt (turquoise, UP-B). a Histograms showing the mean number (N = 3, with error bar indicating standard error of the mean) of non-redundant peptides identified (tot) and annotated at different levels (PF protein family; KO KEGG ortholog; EC enzyme code; BP Gene Ontology Biological Process; PW pathway; *p < 0.05; **p < 0.01; ***p < 0.001; paired t test) in human (left) and mouse (right) samples upon a blastp against bacterial Swiss-Prot entries. b PCA plots of function abundances, with each dot indicating a different human (left) or mouse (right) subject

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