Fig. 6From: The impact of sequence database choice on metaproteomic results in gut microbiota studiesFunctional annotation of human and mouse gut metaproteomic data obtained using different databases. DBs were made up of reads (dark blue, R-A) or contigs (red, C-A) from gut metagenomes of all subjects analyzed for each host species, or all bacterial sequences deposited in UniProt (turquoise, UP-B). a Histograms showing the mean number (N = 3, with error bar indicating standard error of the mean) of non-redundant peptides identified (tot) and annotated at different levels (PF protein family; KO KEGG ortholog; EC enzyme code; BP Gene Ontology Biological Process; PW pathway; *p < 0.05; **p < 0.01; ***p < 0.001; paired t test) in human (left) and mouse (right) samples upon a blastp against bacterial Swiss-Prot entries. b PCA plots of function abundances, with each dot indicating a different human (left) or mouse (right) subjectBack to article page