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Table 2 Permutational multivariate analysis of variance (PERMANOVA) tests of the gut mycobiota on the unweighted and weighted UniFrac distances and the Bray-Curtis dissimilarity according to individuals’ health status and constipation

From: Altered gut microbiota in Rett syndrome

 

Metric

F

R 2

p value*

HC (n = 28)

vs

RTT (n = 49)

Unweighted UniFrac

2.76

0.03

0.006

 

Weighted UniFrac

7.45

0.09

≤0.003

 

Bray-Curtis

6.84

0.08

0.006

HC (n = 28)

vs

RTT-C (n = 33)

Unweighted UniFrac

2.23

0.03

0.018

 

Weighted UniFrac

5.60

0.08

0.009

 

Bray-Curtis

5.82

0.08

≤0.003

HC (n = 28)

vs

RTT-NC (n = 14)

Unweighted UniFrac

2.00

0.04

0.036

 

Weighted UniFrac

5.95

0.12

≤0.003

 

Bray-Curtis

4.59

0.10

0.006

RTT-C (n = 33)

vs

RTT-NC (n = 14)

Unweighted UniFrac

1.01

0.02

1.000

 

Weighted UniFrac

1.27

0.02

0.837

 

Bray-Curtis

1.00

0.02

1.000

  1. HC healthy controls, RTT-C constipated Rett syndrome subjects, RTT-NC non-constipated Rett syndrome subjects
  2. *Bonferroni corrected p values